APPRECIATION OF THE SIGNIFICANCE OF CYTOGENETIC AND FISH ANALYSIS OF BONE-MARROW IN CLINICAL ONCOLOGY

被引：26

作者：

CHEN, Z ^{[1
]}

MORGAN, R ^{[1
]}

STONE, JF ^{[1
]}

SANDBERG, AA ^{[1
]}

机构：

[1] SW BIOMED RES INST & GENETRIX INC,CTR CANC,SCOTTSDALE,AZ 85251

来源：

CANCER GENETICS AND CYTOGENETICS | 1994年 / 78卷 / 01期

关键词：

D O I：

10.1016/0165-4608(94)90039-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Due to some empiric reasons, bone marrow (BM) has never been emphasized and appreciated as a valuable alternative source for metaphases of tumor nature. In the present study, we report the cytogenetic and fluorescence in situ hybridization (FISH) studies of BM in 172 patients with various tumors. Our results indicate that cytogenetic and FISH analyses of BM provide a valuable biologic approach concerning the diagnosis of tumors, evaluation of metastasis, and assessment of secondary hematologic malignancies. Thus, we suggest strongly that these studies become a standard part of clinical pathologic investigations in dealing with clinical oncology.

引用

页码：10 / 14

页数：5

共 17 条

[1]

BOSL GJ, 1989, J NATL CANCER I, V81, P1874

[2] LEUKEMIC DIFFERENTIATION OF A MEDIASTINAL GERM-CELL TUMOR [J].

CHAGANTI, RSK ;

LADANYI, M ;

SAMANIEGO, F ;

OFFIT, K ;

REUTER, VE ;

JHANWAR, SC ;

BOSL, GJ .

GENES CHROMOSOMES & CANCER, 1989, 1 (01) :83-87

[3] APPLICATION OF FLUORESCENCE INSITU HYBRIDIZATION IN HEMATOLOGICAL DISORDERS [J].

CHEN, Z ;

MORGAN, R ;

BERGER, CS ;

SANDBERG, AA .

CANCER GENETICS AND CYTOGENETICS, 1992, 63 (01) :62-69

[4] TRANSLOCATION T(3-21)(Q26-Q22) IN ACUTE MYELOBLASTIC-LEUKEMIA SECONDARY TO POLYCYTHEMIA-VERA [J].

DASTUGUE, N ;

PRIS, J ;

COLOMBIES, P .

CANCER GENETICS AND CYTOGENETICS, 1990, 44 (02) :275-276

[5] PATHOGENESIS OF ADULT TESTICULAR GERM-CELL TUMORS - A CYTOGENETIC MODEL [J].

DEJONG, B ;

OOSTERHUIS, JW ;

CASTEDO, SMMJ ;

VOS, A ;

TEMEERMAN, GJ .

CANCER GENETICS AND CYTOGENETICS, 1990, 48 (02) :143-167

[6] ASSOCIATION BETWEEN MEDIASTINAL GERM-CELL TUMORS AND HEMATOLOGIC MALIGNANCIES - REPORT OF 2 CASES AND REVIEW OF THE LITERATURE [J].

DEMENT, SH ;

EGGLESTON, JC ;

SPIVAK, JL .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1985, 9 (01) :23-30

[7]

DIETSCHY JM, 1980, SCI PRACTICE CLIN ME, P251

[8] MULTIPLE CLONES WITH (3-21) TRANSLOCATION IN A CASE OF PH-POSITIVE CHRONIC MYELOGENOUS LEUKEMIA DURING RELAPSE AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION [J].

GILLILAND, G ;

PATTERSON, EJ ;

ROSENTHAL, DS ;

TANTRAVAHI, R .

CANCER GENETICS AND CYTOGENETICS, 1990, 47 (01) :55-60

[9] CYTOGENETIC FINDINGS IN PRIMARY AND SECONDARY MDS [J].

HEIM, S .

LEUKEMIA RESEARCH, 1992, 16 (01) :43-46

[10]

JENS PB, 1989, EUR J HAEMAT, V42, P39

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