SYSTEMATIC REPRESENTATION OF PROTEIN-FOLDING PATTERNS
被引:28
作者:
LESK, AM
论文数: 0引用数: 0
h-index: 0
机构:Department of Haematology, University of Cambridge Clinical School, MRC Centre, Cambridge
LESK, AM
机构:
[1] Department of Haematology, University of Cambridge Clinical School, MRC Centre, Cambridge
来源:
JOURNAL OF MOLECULAR GRAPHICS
|
1995年
/
13卷
/
03期
关键词:
PROTEIN STRUCTURE;
TOPOLOGY;
FOLDING PATTERN;
CLASSIFICATION;
TABLEAU REPRESENTATION;
D O I:
10.1016/0263-7855(95)00037-7
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
A tabular representation of protein folding patterns is described, which comprises information about the order along the chain of helices and strands of sheer, identifies the elements of secondary structure that interact, and indicates their relative orientation. These tableaux are intelligible to both people and computers, and support the application of algorithms for identification of proteins with similar folding patterns. Their inclusion in a database of protein structures would support investigations of structural relationships at the topological level.