Reaction of 3-phenyl-5-aminopyrazole with carbon disulfide: A novel synthesis of 3-(3'-phenylpyrazol-5'-yl)-4-phenylpyrazol-2-thione as well as of pyrazolo[3,4-d]thiazole and pyrano[2,3-d]thiazole derivatives

被引：16

作者：

Mohareb, RM

Zohdi, HF

Wardakhan, WW

机构：

[1] Chemistry Department, Faculty of Science, Cairo University, Giza

来源：

MONATSHEFTE FUR CHEMIE | 1995年 / 126卷 / 12期

关键词：

aminopyrazole; pyrazolo[3,4-d]thiazole; pyrano[2,3-d]thiazole;

D O I：

10.1007/BF00807069

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-Phenyl-5-aminopyrazole (1) reacts with carbon disulfide, followed by in situ reaction with alpha-halokerones 3a-c, to afford 5, 7a, and 7b, respectively. Compounds 5 and 7 were further utilized for the formation of heterocycles and their fused derivatives.

引用

页码：1391 / 1400

页数：10

共 12 条

[1]

ANDOLSEK A, 1971, J MED CHEM, V14, P53

[2]

BHARAGAVA PN, 1926, B CHEM SOC JPN, V35, P1926

[3]

Burger A., 1945, MED CHEM, P345

[4] STRUCTURAL MODIFICATION STUDIES OF 3-PIPERONYLSYDNONE .2. SYNTHESIS OF PIPERONYL-SUBSTITUTED HYDANTOIN, THIOHYDANTOIN, THIAZOLIDINEDIONE, RHODANINE, IMIDAZOLINONE, AND RELATED COMPOUNDS [J].