VENTROMEDIAL HYPOTHALAMIC LESIONS AND CHANGES IN BODY WEIGHT AND FOOD CONSUMPTION IN MALE AND FEMALE RATS

Ventromedial hypothalamic (VMH) lesions had differential effects in 23 male and 20 female Holtzman albino rats. When males and females were matched for either age or weight, lesioned females displayed greater hyperphagia and weight gain than males. Extensive bilateral VMH damage resulted in diminished rate of weight gain in males, in spite of increased food intake. (22 ref.) (PsycINFO Database Record (c) 2006 APA, all rights reserved). © 1969 American Psychological Association.