2 NOVEL INDOLE REARRANGEMENTS

被引：13

作者：

ACHESON, RM

PRINCE, RJ

PROCTER, G

机构：

[1] Department of Biochemistry, Oxford OX1 3QU, South Parks Road

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1979年 / 03期

关键词：

D O I：

10.1039/p19790000595

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ethyl 3-methylindole-2-carboxylate is rearranged by sulphuryl chloride to ethyl 3-methyl-2-oxoindoline-3-carboxylate, and similar transformations accompanied by halogenation are effected by bromine, or ethyl NN-dichlorocarbamate, in aqueous acetic acid. The last reagent converted both NN-dimethylindole-2- and -3-carboxamides into 3,5,7-trichloro-NN-dimethyl-2- oxoindoline-3-carboxamide.

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页码：595 / 598

页数：4

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