TREATMENT OF EXPERIMENTAL CHRONIC OSTEOMYELITIS DUE TO STAPHYLOCOCCUS-AUREUS WITH AMPICILLIN SULBACTAM

被引：14

作者：

NORDEN, CW

BUDINSKY, A

机构：

[1] Department of Medicine, Montefiore Hospital, University of Pittsburgh School of Medicine, PA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1990年 / 161卷 / 01期

关键词：

D O I：

10.1093/infdis/161.1.52

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ampicillin/sulbactam was used for the treatment of experimental osteomyelitis due to Staphylococcus aureus in rabbits. Treatment with 200 mg/kg (ampicillin) three times a day sterilized 40% of infected rabbit bones. The results of 4 weeks of treatment with ampicillin/sulbactam for chronic experimental staphylococcal osteomyelitiswere comparable to those obtained previously with cephalothin and with oxacillin in previous studies and were not as good as those with clindamycin alone or combination therapy that included rifampin. © 1990 by The University of Chicago. All rights reserved.

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页码：52 / 53

页数：2

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