PARALLEL ORIENTATION OF FIBROBLASTS IN VITRO

被引：54

作者：

ELSDALE, TR

机构：

[1] Medical Research Council, Western General Hospital, Edinburgh 4, Scotland

来源：

EXPERIMENTAL CELL RESEARCH | 1968年 / 51卷 / 2-3期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0014-4827(68)90134-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

1. 1. Obervations have been made on the generation of parallel arrangements among human, foetal, diploid, lung fibroblasts in Petri dish cultures initiated randomly from cell suspensions, and maintained without subculturing for several weeks or months. 2. 2. The mechanism by which the cells become aligned has been investigated using time-lapse microcinema-photography, autoradiography, and the enzyme collagenase. 3. 3. An explanation for the generation and maintenance of the parallel arrangement in fibroblast cultures is given in terms of the parallel arrangement being the configuration that allows the maximum exercise of cell motility in dense cultures. © 1968.

引用

页码：439 / &

共 13 条

[1]

ABERCROMBIE M, 1962, CANCER RES, V22, P525

[2]

ABERCROMBIE M, 1965, CELLS TISSUE CULT, V1, P177

[3]

CURTIS AS, 1961, J NATL CANCER I, V26, P253

[4]

FEDEROFF S, 1967, EXP CELL RES, V46, P642

[5] CLONAL GROWTH OF DIPLOID CHINESE HAMSTER CELLS IN A SYNTHETIC MEDIUM SUPPLEMENTED WITH PURIFIED PROTEIN FRACTIONS [J].