GENERATION OF FACTOR-VIII COAGULANT ACTIVITY BY ISOLATED, PERFUSED NEONATAL PIG LIVERS AND ADULT-RAT LIVERS

被引：30

作者：

OWEN, CA ^{[1
]}

BOWIE, EJW ^{[1
]}

FASS, DN ^{[1
]}

机构：

[1] MAYO CLIN & MAYO FDN, DEPT HEMATOL RES, ROCHESTER, MN 55901 USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1979年 / 43卷 / 02期

关键词：

D O I：

10.1111/j.1365-2141.1979.tb03754.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Summary. Isolated, normal, neonatal pig livers released VIII:C into perfusates of porcine von Willebrand blood lacking VIIIR:AG and VIII:RWF. Neonatal von Willebrand livers released VIII:C only when partially purified VIIIR:AG was added to the von Willebrand blood. Adult rat livers, perfused with frozen‐thawed erythrocytes suspended in Tyrode's solution containing 6% bovine serum albumin and hence no VIIIR:AG released VIII:C only when serum, adsorbed serum or cryoprecipitate from rat plasma was added to the perfusate. Cycloheximide blocked the release of VIII:C from rat liver. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：307 / 315

页数：9

共 67 条

[1] KIDNEY ANTIHEMOPHILIC FACTOR . PARTIAL PURIFICATION AND SOME PROPERTIES [J].

BARROW, EM ;

GRAHAM, JB .

BIOCHEMISTRY, 1968, 7 (11) :3917-&

[2]

BARROW EM, 1969, FED PROC, V28, P746

[3] ALBUMIN AND COAGULATION-FACTOR VIII (AHF) [J].

BARROW, ES ;

GRAHAM, JB .

AMERICAN JOURNAL OF PHYSIOLOGY, 1974, 227 (02) :412-419

[4] THE PURIFICATION OF BOVINE ANTI-HEMOPHILIC GLOBULIN [J].

BIDWELL, E .

BRITISH JOURNAL OF HAEMATOLOGY, 1955, 1 (01) :35-45

[5]

BLOOM AL, 1973, LANCET, V1, P661

[6] FACTOR-VIII ON VASCULAR INTIMA - POSSIBLE IMPORTANCE IN HEMOSTASIS AND THROMBOSIS [J].

BLOOM, AL ;

GIDDINGS, JC ;

WILKS, CJ .

NATURE-NEW BIOLOGY, 1973, 241 (111) :217-219

[7]

BOLDYREFF WN, 1937, TOHOKU J EXP MED, V31, P469

[8] CULTURED AORTIC ENDOTHELIAL CELLS FROM PIGS WITH VONWILLEBRAND DISEASE - INVITRO MODEL FOR STUDYING MOLECULAR DEFECT(S) OF DISEASE [J].

BOOYSE, FM ;

QUARFOOT, AJ ;

BELL, S ;

FASS, DN ;

LEWIS, JC ;

MANN, KG ;

BOWIE, EJW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5702-5706

[9]

BOUMA BN, 1973, LANCET, V1, P1001

[10] LIVER-TRANSPLANTATION IN PIGS WITH VONWILLEBRANDS DISEASE [J].

BOWIE, EJW ;

WOODS, JE ;

FASS, DN ;

ZOLLMAN, PE ;

OWEN, CA .

BRITISH JOURNAL OF HAEMATOLOGY, 1975, 31 (01) :37-44

← 1 2 3 4 5 6 7 →