ALKYLATION OF THE CYCLIC SULFAMATE OF PROLINOL - PREPARATION OF OPTICALLY-ACTIVE 2-ALKYL-SUBSTITUTED PYRROLIDINES

被引：24

作者：

COOPER, GF

MCCARTHY, KE

MARTIN, MG

机构：

[1] Institute of Organic Chemistry, Syntex Research, Palo Alto, CA 94304

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(00)61082-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of the cyclic sulfamate of (R)-prolinol (1) with aromatic lithium reagents, followed by acidic hydrolysis, gives 2-substituted pyrrolidines 3a-c in moderate yields.

引用

页码：5895 / 5896

页数：2

共 7 条

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