ATRAZINE IN PLASMA AND TISSUE FOLLOWING ATRAZINE-AMINOTRIAZOLE-ETHYLENE GLYCOL-FORMALDEHYDE POISONING

被引：16

作者：

POMMERY, J

MATHIEU, M

MATHIEU, D

LHERMITTE, M

机构：

[1] CHR LILLE,CTR ANTI POISON,F-59037 LILLE,FRANCE

[2] HOP CALMETTE,SERV REANIMAT,LILLE,FRANCE

来源：

JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY | 1993年 / 31卷 / 02期

关键词：

ATRAZINE; CHROMATOGRAPHY; HIGH PRESSURE LIQUID; TISSUE DISTRIBUTION; METABOLIC DETOXICATION; PHARMACOKINETICS; HERBICIDES; TRIAZINE; METABOLIC CLEARANCE RATE;

D O I：

10.3109/15563659309000399

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

A high performance liquid chromatography method has been used to study the plasma kinetics of atrazine in a human fatality after ingestion of a herbicide mix containing atrazine, aminotriazole, ethylene glycol and formaldehyde. A hemodialysis was performed in an effort to eliminate these toxic substances. The mean atrazine clearance over 4 h was 250 mL/min and the dialysance of atrazine was calculated as 76%. On autopsy, the kidney showed the highest concentration of atrazine (97.62 mug/g-1 wet tissue) with lesser concentrations in the lung, small intestine and liver, and the lowest concentration in the heart.

引用

页码：323 / 331

页数：9

共 7 条

[1] ATRAZINE HYDROLYSIS IN SOIL [J].