A NOVEL MODEL OF A METASTATIC HUMAN BREAST-TUMOR XENOGRAFT LINE

被引：37

作者：

HURST, J

MANIAR, N

TOMBARKIEWICZ, J

LUCAS, F

ROBERSON, C

STEPLEWSKI, Z

JAMES, W

PERRAS, J

机构：

[1] WISTAR INST ANAT & BIOL,PHILADELPHIA,PA 19104

[2] CLEVELAND CLIN,FT LAUDERDALE,FL

[3] ONCOR INC,GAITHERSBURG,MD

[4] UNIV MIAMI,SCH MED,DEPT GYNECOL ONCOL,MIAMI,FL 33152

来源：

BRITISH JOURNAL OF CANCER | 1993年 / 68卷 / 02期

关键词：

D O I：

10.1038/bjc.1993.327

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The GI-101 human breast tumour xenograft-line is unique in that it spontaneously metastasises to the lungs of athymic murine hosts from subcutaneous trochar implants. Both tumour and lung metastases are positive for normal human breast tissue markers. GI-101 also is positive for the p53 antigen but negative for the c-erbB-2 oncogene.

引用

页码：274 / 276

页数：3

共 5 条

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[2] HETEROTRANSPLANTATION OF HUMAN BREAST CARCINOMAS IN NUDE-MICE - CORRELATION BETWEEN SUCCESSFUL HETEROTRANSPLANTS, POOR PROGNOSIS AND AMPLIFICATION OF THE HER-2 NEU ONCOGENE [J].