NUMERICAL ABERRATIONS, INCLUDING TRISOMY-22 AS THE SOLE ANOMALY, ARE RECURRENT IN FOLLICULAR THYROID ADENOMAS

被引：23

作者：

ANTONINI, P

LEVY, N

CAILLOU, B

VENUAT, AM

SCHLUMBERGER, M

PARMENTIER, C

BERNHEIM, A

机构：

[1] INST GUSTAVE ROUSSY,CYTOGENET & GENET ONCOL LAB,CNRS,URA 1158,PR2,F-94805 VILLEJUIF,FRANCE

[2] INST GUSTAVE ROUSSY,INSERM,U66,F-94805 VILLEJUIF,FRANCE

[3] INST GUSTAVE ROUSSY,ANAT PATHOL LAB,F-94805 VILLEJUIF,FRANCE

来源：

GENES CHROMOSOMES & CANCER | 1993年 / 8卷 / 01期

关键词：

D O I：

10.1002/gcc.2870080111

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Short-term cultures from 38 follicular thyroid adenomas revealed clonal numerical and/or structural chromosomal changes in 8 tumors, nonclonal changes in 1 tumor, and only normal karyotypes in 29 tumors. Three cases had trisomy 22 as the sole anomaly. Two cases had a combination of trisomies for chromosomes 5, 7, 9, 12, and 16. (C) 1993 Wiley-Liss, Inc.

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页码：63 / 66

页数：4

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