PALLADIUM-CATALYZED COUPLING OF HETEROAROMATIC TRIFLATES WITH ACETYLENE AND ITS APPLICATION FOR A DYNEMICIN-A INTERMEDIATE

被引:40
作者
OKITA, T [1 ]
ISOBE, M [1 ]
机构
[1] NAGOYA UNIV,SCH AGR SCI,ORGAN CHEM LAB,NAGOYA,AICHI 46401,JAPAN
关键词
D O I
10.1016/0040-4020(95)00118-R
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An acetylene moiety was introduced to a carbonyl carbon of amide group via its triflate in the presence of palladium catalyst, The reaction proceeded smoothly under mild conditions. Utilizing this methodology, a model compound of dynemicin A bearing acetylene group was synthesized.
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页码:3737 / 3744
页数:8
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