KETENE DITHIOACETALS .2. CONTROL OF ALPHA VS GAMMA-ALLYLATION USING CUPROUS SALTS

Ketene dithioacetals have recently received attention as viable synthetic intermediates.3 It has been demonstrated184 that their lithium anions undergo a alkylation to provide the dithianes of α, β-unsaturated ketones. We have sought to control the y alkylation of these anions, thereby allowing them to serve as d-propionate anion equivalents.5 Efforts to control α vs. 73x03B3; alkylation in heteroatom-stabilized allylic anions186 and resonance. © 1979, American Chemical Society. All rights reserved.