ELECTROCONVULSIVE-THERAPY IN PARKINSONS-DISEASE AND OTHER MOVEMENT-DISORDERS

被引:84
作者
FABER, R
TRIMBLE, MR
机构
[1] Department of Psychiatry, University of Texas Health Science Center at San Antonio and Audie L., Murphy Memorial Veterans Hospital, San Antonio, Texas
[2] National Hospitals, Institute of Neurology, London, Queen Square
关键词
ELECTROCONVULSIVE THERAPY; MOVEMENT DISORDERS; PARKINSONS DISEASE;
D O I
10.1002/mds.870060405
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Early case reports note marked improvements in the signs of Parkinson' s disease (PD) in several patients with coexisting psychiatric disorders after treatment with electroconvulsive therapy (ECT). Studies since 1959 reveal improvement of parkinsonism in over half of PD patients receiving ECT, regardless of the presence or absence of psychiatric comorbidity. Drug-induced parkinsonism, tardive dystonia, and tardive dyskinesia have also been shown to improve with ECT administration; tic syndromes have achieved mixed results. In animals, ECT enhances dopamine-mediated effects and increases GABA concentrations in the CNS. Optimal parameters relevant to the antiparkinsonism effects of ECT require further study.
引用
收藏
页码:293 / 303
页数:11
相关论文
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