PHYLOGENY OF VIROIDS, VIROID-LIKE SATELLITE RNAS, AND THE VIROID-LIKE DOMAIN OF HEPATITIS DELTA VIRUS-RNA

被引：86

作者：

ELENA, SF

DOPAZO, J

FLORES, R

DIENER, TO

MOYA, A

机构：

[1] UNIV VALENCIA,DEPT GENET,DR MOLINER 50,E-46100 BURJASSOT,SPAIN

[2] CSIC,INST AGROQUIM & TECNOL ALIMENTOS,UNIDAD BIOL MOLEC & CELULAR PLANTAS,E-46010 VALENCIA,SPAIN

[3] UNIV MARYLAND,CTR AGR BIOTECHNOL,COLLEGE PK,MD 20742

[4] UNIV MARYLAND,DEPT BOT,COLLEGE PK,MD 20742

[5] USDA ARS,BELTSVILLE AGR RES CTR,BELTSVILLE,MD 20705

[6] UNIV VALENCIA,SERV BIOINFORMAT,E-46100 BURJASSOT,SPAIN

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1991年 / 88卷 / 13期

关键词：

STATISTICAL GEOMETRY; QUASISPECIES; RNA WORLD; LIVING FOSSILS;

D O I：

10.1073/pnas.88.13.5631

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We report a phylogenetic study of viroids, some plant satellite RNAs, and the viroidlike domain of human hepatitis-delta-virus RNA. Our results support a monophyletic origin of these RNAs and are consistent with the hypothesis that they may be "living fossils" of a precellular RNA world. Moreover, the viroidlike domain of human hepatitis-delta-virus RNA appears closely related to the viroidlike satellite RNAs of plants, with which it shares some structural and functional properties. On the basis of our phylogenetic analysis, we propose a taxonomic classification of these RNAs.

引用

页码：5631 / 5634

页数：4

共 50 条

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