ADRENAL TYROSINE HYDROXYLASE - COMPENSATORY INCREASE IN ACTIVITY AFTER CHEMICAL SYMPATHECTOMY

被引：202

作者：

MUELLER, RA

THOENEN, H

AXELROD, J

机构：

[1] Laboratory of Clinical Science, National Institute of Mental Health, Bethesda

[2] Hoffmann-La Roche, Basel

来源：

SCIENCE | 1969年 / 163卷 / 3866期

关键词：

D O I：

10.1126/science.163.3866.468

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Destruction of peripheral sympathetic nerve endings with 6-hydroxydopamine causes a disappearance of cardiac tyrosine hydroxylase, accompanied by a twofold increase in adrenal tyrosine hydroxylase and a small increase in phenyl-ethanolamine-N-methyl transferase. No change in adrenal catecholamine content occurs under these conditions.

引用

页码：468 / &

共 12 条

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[4] HAUSLER G, IN PRESS
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[9] INFLUENCE OF SYMPATHETIC DENERVATION AND NERVE IMPULSE ACTIVITY OF TYROSINE HYDROXYLASE IN RAT SUBMAXILLARY GLAND
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KOPIN, IJ
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[10] CHEMICAL SYMPATHECTOMY BY SELECTIVE DESTRUCTION OF ADRENERGIC NERVE ENDINGS WITH 6-HYDROXYDOPAMINE
THOENEN, H
TRANZER, JP
[J]. NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE, 1968, 261 (03): : 271 - &

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