DEVELOPMENT, PREPARATION AND SAFETY TESTING OF A CLOSTRIDIUM-WELCHII TYPE-C TOXOID .1. PRELIMINARY-OBSERVATIONS IN MAN IN PAPUA-NEW-GUINEA

被引:18
作者
WALKER, PD [1 ]
FOSTER, WH [1 ]
KNIGHT, PA [1 ]
FREESTONE, DS [1 ]
LAWRENCE, G [1 ]
机构
[1] INST MED RES, GOROKA, PAPUA N GUINEA
来源
JOURNAL OF BIOLOGICAL STANDARDIZATION | 1979年 / 7卷 / 04期
关键词
D O I
10.1016/S0092-1157(79)80006-2
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The reactogenicity and immunogenicity of various strengths of plain and adsorbed Cl. welchii type C toxoid have been evaluated in laboratory tests and in man in Papua New Guinea. The greater antigenicity and acceptable clinical reactivity of a vaccine containing 50 total combining power units per 0-5 mm of adsorbed toxoid resulted in its selection for further field studies. © 1979 The International Association of Biological Standardization.
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收藏
页码:315 / 323
页数:9
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