FIRST CATALYTIC AND ENANTIOSELECTIVE SYNTHESIS OF SILYL AND STANNYL SUBSTITUTED CYCLOPROPYLMETHANOLS

被引：63

作者：

IMAI, N ^{[1
]}

SAKAMOTO, K ^{[1
]}

TAKAHASHI, H ^{[1
]}

KOBAYASHI, S ^{[1
]}

机构：

[1] SAGAMI CHEM RES CTR,SAGAMIHARA,KANAGAWA 229,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 38期

关键词：

D O I：

10.1016/0040-4039(94)88221-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active silyl and stannyl substituted cyclopropylmethanols were effectively obtained by the catalytic and enantioselective cyclopropanation of gamma-silyl and gamma-stannyl substituted allylic alcohols with Et(2)Zn and CH2I2 in the presence of chiral N,N'-bis(p-nitrobenzenesulfonyl) -1,2 -cyclohexanediamine in goad enantioselectivites. The absolute configurations of the resulting metallocyclopropanes were unambiguously established.

引用

页码：7045 / 7048

页数：4

共 7 条

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