GAMMA-IRRADIATION OF CARBOXYMETHYLCELLULOSE - TECHNOLOGICAL AND PHARMACEUTICAL ASPECTS

被引：11

作者：

SEBERT, P

BOURNY, E

ROLLET, M

机构：

[1] Laboratoire de Pharmacie Galénique Industrielle et Biogalénique, Faculté de Pharmacie, I.S.P.B., Domaine Rockefeller

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1994年 / 106卷 / 02期

关键词：

SODIUM CARBOXYMETHYLCELLULOSE; GAMMA IRRADIATION; PHYSICAL PROPERTIES; RHEOLOGY; BINDING AGENT;

D O I：

10.1016/0378-5173(94)90307-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In this work, we have studied the stability of sodium carboxymethylcellulose (NaCMC) powder after irradiation. Its effect on the physical, chemical and pharmacotechnical properties has been investigated in order to determine the influence of such treatment on the functional properties of NaCMC, especially on the formulation of gels, suspensions, tablets and sustained release parenteral dosage forms.

引用

页码：103 / 108

页数：6