EFFECT OF RADIATION ON GROWTH OF VERTEBRAE IN TAILS OF RATS .2. SPLIT DOSES OF X-RAYS AND EFFECT OF OXYGEN

被引：10

作者：

DIXON, B

机构：

[1] Experimental Radiopathology Research Unit, Medical Research Council, Hammersmith Hospital

[2] Department of Experimental Pathology and Cancer Research, The School of Medicine, Leeds University

来源：

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY AND RELATED STUDIES IN PHYSICS CHEMISTRY AND MEDICINE | 1969年 / 15卷 / 03期

关键词：

D O I：

10.1080/09553006914550391

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Vertebrae in the tails of rats have been irradiated with single and split doses of x-rays under reduced, normal and increased conditions of oxygenation. Split doses were less effective in stunting vertebral growth than single doses. This sparing effect was dependent on the time between fractions and the size of the total dose, but independent of vertebral oxygenation. These results are accounted for in terms of the recovery of epiphyseal cartilage cells from sublethal injury. It is suggested that with x-rays the survival curve for epiphyseal cells in situ has a large shoulder followed by an exponential part. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：215 / &

共 33 条

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