INHIBITION OF BETA-D-GALACTOSIDASES BY D-GALACTAL

被引：69

作者：

LEE, YC

机构：

[1] Department of Biology, The Johns Hopkins University, Balitmore

[2] McCollum-Partt Institute The Johns Hopkins University, Balitmore

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 35卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0006-291X(69)90499-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This report presents evidence indicating that D-galactal (1,2-dideoxy-D-lyxo-hex-1-enopyranose, (I)) is a potent inhibitor of β-D-galactopyranosidases derived from a variety of sources. D-Galactal represents a new type of inhibitor for glycosidases, and it is suggested that the planar half-chair conformation (II or IIa), preferred by D-galactal, is responsible for its inhibitory action. {A figure is presented}. © 1969.

引用

页码：161 / &

共 12 条

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