Steroid and related receptors

被引：189

作者：

Parker, Malcolm G. ^{[1
]}

机构：

[1] Imperial Canc Res Fund, London WC2A 3PX, England

来源：

CURRENT OPINION IN CELL BIOLOGY | 1993年 / 5卷 / 03期

关键词：

D O I：

10.1016/0955-0674(93)90016-J

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Steroid hormone receptors stimulate gene transcription by binding to DNA as homodimers, whereas many other members of the nuclear receptor family appear to function as heterodimers or as monomers. This is important for target gene recognition and, given that many of the receptors are expressed in multiple forms, generates many combinations of ligand-dependent transcription factors that regulate the expression of different genes in diverse pathways.

引用

页码：499 / 504

页数：6

共 35 条

[1] THE ORIGIN OF NUCLEAR RECEPTOR PROTEINS - A SINGLE PRECURSOR DISTINCT FROM OTHER TRANSCRIPTION FACTORS
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[5] CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR (COUP-TF) DIMERS BIND TO DIFFERENT GGTCA RESPONSE ELEMENTS, ALLOWING COUP-TF TO REPRESS HORMONAL INDUCTION OF THE VITAMIN-D(3), THYROID-HORMONE, AND RETINOIC ACID RECEPTORS
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[6] IDENTIFICATION OF A CONSERVED REGION REQUIRED FOR HORMONE DEPENDENT TRANSCRIPTIONAL ACTIVATION BY STEROID-HORMONE RECEPTORS
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[J]. EMBO JOURNAL, 1992, 11 (03) : 1025 - 1033
[7] PROTEIN PHOSPHATASE TYPES-1 AND OR 2A REGULATE NUCLEOCYTOPLASMIC SHUTTLING OF GLUCOCORTICOID RECEPTORS
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[J]. MOLECULAR ENDOCRINOLOGY, 1991, 5 (09) : 1215 - 1228
[8] NOVEL GLUCOCORTICOID RECEPTOR COMPLEX WITH DNA ELEMENT OF THE HORMONE-REPRESSED POMC GENE
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[9] ALL-TRANS AND 9-CIS RETINOIC ACID INDUCTION OF CRABPII TRANSCRIPTION IS MEDIATED BY RAR-RXR HETERODIMERS BOUND TO DR1 AND DR2 REPEATED MOTIFS
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[J]. EMBO JOURNAL, 1991, 10 (12) : 3851 - 3859

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