ZINC-FREE CUBIC PIG INSULIN - CRYSTALLIZATION AND STRUCTURE DETERMINATION

被引：58

作者：

DODSON, EJ ^{[1
]}

DODSON, GG ^{[1
]}

LEWITOVA, A ^{[1
]}

SABESAN, M ^{[1
]}

机构：

[1] UNIV OXFORD,MOLEC BIOPHYS LAB,OXFORD,ENGLAND

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1978年 / 125卷 / 03期

关键词：

D O I：

10.1016/0022-2836(78)90409-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Zinc-free cubic pig insulin has been crystallized under conditions which yielded large single crystals. Data were collected to 1.7 Å spacing and the rotation function (Rossmann & Blow, 1962) and translation search used to determine phases. The resulting maps indicate that this phase set can be used as a starting point for refinement of the structure. © 1978.

引用

页码：387 / 396

页数：10

共 15 条

[1] Abel JJ, 1927, J PHARMACOL EXP THER, V31, P65
[2] [Anonymous], 1972, ADV PROTEIN CHEM
[3] STRUCTURE OF INSULIN IN 4-ZINC INSULIN
BENTLEY, G
DODSON, E
DODSON, G
HODGKIN, D
MERCOLA, D
[J]. NATURE, 1976, 261 (5556) : 166 - 168
[4] LOW RESOLUTION CRYSTAL-STRUCTURE OF HAGFISH INSULIN
CUTFIELD, JF
CUTFIELD, SM
DODSON, EJ
DODSON, GG
SABESAN, MN
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1974, 87 (01) : 23 - 30
[5] CUTFIELD SM, 1975, THESIS OXFORD U
[6] FRENCH S, 1975, THESIS OXFORD U
[7] STRUCTURE OF A SILICON CARBIDE POLYTYPE 24R
HAMILTON, WC
ROLLETT, JS
SPARKS, RA
[J]. ACTA CRYSTALLOGRAPHICA, 1965, 18 : 129 - &
[8] CRYSTAL STRUCTURE OF INSULIN .2. AN INVESTIGATION OF RHOMBOHEDRAL ZINC INSULIN CRYSTALS AND A REPORT OF OTHER CRYSTALLINE FORMS
HARDING, MM
HODGKIN, DC
KENNEDY, AF
OCONNOR, A
WEITZMANN, PD
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1966, 16 (01) : 212 - +
[9] Jackson R. L., 1974, US Patent, Patent No. 3856771
[10] SOLVENT CONTENT OF PROTEIN CRYSTALS
MATTHEWS, BW
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1968, 33 (02) : 491 - +

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