TANDEM MICHAEL REACTIONS FOR THE CONSTRUCTION OF PYRROLIDINE AND PIPERIDINE RING-SYSTEMS

被引：26

作者：

BARCO, A ^{[1
]}

BENETTI, S ^{[1
]}

CASOLARI, A ^{[1
]}

POLLINI, GP ^{[1
]}

SPALLUTO, G ^{[1
]}

机构：

[1] DIPARTIMENTO SCI FARMACEUT,I-44100 FERRARA,ITALY

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)89020-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convergent one-pot construction of disubstituted pyrrolidine and piperidine frameworks has been accomplished through a simple protocol involving intermolecular conjugate addition of a nitrogen nucleophile to an electrophilic olefin followed by intramolecular trapping of the generated enolate by a built-in α,β,-unsaturated acceptor. © 1990.

引用

页码：3039 / 3042

页数：4

共 29 条

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[2] CHIRAL SYNTHESIS OF 5-HYDROXY-(L)-PIPECOLIC ACIDS FROM (L)-GLUTAMIC ACID
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[3] COBALT-MEDIATED CYCLIZATION OF AMINO-ACID DERIVATIVES - APPLICATION TO THE KAINOIDS
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[4] ENANTIOSPECIFIC SYNTHESIS OF ACROMELIC ACID-A VIA A COBALT-MEDIATED CYCLIZATION REACTION
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[6] ENANTIOSPECIFIC SYNTHESES OF 2S,3R,4R,5S-TRIHYDROXYPIPECOLIC ACID, 2R,3R,4R,5S-TRIHYDROXYPIPECOLIC ACID, 2S,4S,5S-DIHYDROXYPIPECOLIC ACID, AND BULGECININE FROM DEUTERIUM-GLUCURONOLACTONE
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[J]. TETRAHEDRON LETTERS, 1986, 27 (27) : 3205 - 3208
[7] TANDEM MICHAEL REACTIONS FOR THE CONSTRUCTION OF HIGHLY FUNCTIONALIZED 5-MEMBERED RINGS
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WAMSLEY, EJ
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[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (03) : 464 - 466
[8] A TOTAL SYNTHESIS OF (+/-)-ALLO-KAINIC ACID
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KELL, DA
[J]. TETRAHEDRON LETTERS, 1986, 27 (34) : 3979 - 3982
[9] ASYMMETRIC-SYNTHESIS .10. A CHIRAL PYRROLIDINE SYNTHON FOR A NEW APPROACH TO THE SYNTHESIS OF ALKALOIDS
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[J]. TETRAHEDRON LETTERS, 1987, 28 (05) : 547 - 550
[10] UNSYMMETRICAL 2,5-DIALKYLPYRROLIDINES VIA REDUCTIVE AMINATION OF 1,4-DIKETONES
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[J]. TETRAHEDRON LETTERS, 1980, 21 (09) : 789 - 792

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