EFFECTIVENESS OF NAFCILLIN, METHICILLIN, AND CEPHALOTHIN IN EXPERIMENTAL STAPHYLOCOCCUS-AUREUS ENDOCARDITIS

被引：25

作者：

CARRIZOSA, J ^{[1
]}

KOBASA, WD ^{[1
]}

KAYE, D ^{[1
]}

机构：

[1] MED COLL PENN,DEPT MED,PHILADELPHIA,PA 19129

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1979年 / 15卷 / 05期

关键词：

D O I：

10.1128/AAC.15.5.735

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Nafcillin, methicillin, and cephalothin (40 mg/kg every 6 hr were all effective in reducing the number of Staphylococcus aureus in vegetations in rabbits with endocarditis. Nafcillin and methicillin reduced the number of S. aureus at a significantly faster rate than did cephalothin. Nafcillin and methicillin also reduced titers of the S. aureus more rapidly than did cephalothin in vitro, both in broth and in rabbit serum.

引用

页码：735 / 737

页数：3

共 6 条

[1]

BRAUDE AI, 1976, MAJOR PROB INT MED, V8, P80

[2] TREATMENT OF EXPERIMENTAL STAPHYLOCOCCUS-AUREUS ENDOCARDITIS - COMPARISON OF CEPHALOTHIN, CEFAZOLIN, AND METHICILLIN [J].