INVITRO EPOXIDATION OF ALL-TRANS-RETINOIC ACID IN RAT-TISSUE HOMOGENATES

被引：19

作者：

SIETSEMA, WK

DELUCA, HF

机构：

[1] Department of Biochemistry College of Agricultural, Life Sciences University of Wisconsin-Madison, Madison

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 90卷 / 04期

关键词：

D O I：

10.1016/0006-291X(79)91147-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Rat tissue homogenates catalyze the epoxidation of all-trans-retinoic acid to 5,6-epoxyretinoic acid. Kidney, intestine, and liver are the most active of the tissues examined. Spleen, testes, and brain have some activity, but muscle and lung have little or no activity. Boiled homogenates do not catalyze the reaction. N-propyl gallate inhibits the reaction. The product has been chemically and physically identified as 5,6-epoxyretinoic acid. © 1979.

引用

页码：1091 / 1097

页数：7

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