NONENZYMATIC HYDROLYSIS OF AN RNA-DIMER CONTAINING A THIOPHOSPHATE LINKAGE

被引：3

作者：

ALMER, H ^{[1
]}

STROMBERG, R ^{[1
]}

机构：

[1] UNIV STOCKHOLM,ARRHENIUS LAB,DEPT ORGAN CHEM,S-10691 STOCKHOLM,SWEDEN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期

关键词：

D O I：

10.1080/07328319108046562

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A Diuridine (3'-5')-thiophosphate (1b) was hydrolyzed under basic conditions. The rate of hydrolysis of the uridylyl (3'-5')-uridine (1a) was three times higher compared to that of 1b.

引用

页码：653 / 655

页数：3

共 4 条

[1] NUCLEOSIDE PHOSPHOROTHIOATES
ECKSTEIN, F
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1985, 54 : 367 - 402
[2] KETELAAR JAA, 1952, RECL TRAV CHIM PAY B, V71, P1253
[3] STEREOCHEMISTRY OF RNA CLEAVAGE BY THE TETRAHYMENA RIBOZYME AND EVIDENCE THAT THE CHEMICAL STEP IS NOT RATE-LIMITING
MCSWIGGEN, JA
CECH, TR
[J]. SCIENCE, 1989, 244 (4905) : 679 - 683
[4] RATE-LIMITING STEPS IN THE DNA-POLYMERASE-I REACTION PATHWAY
MIZRAHI, V
HENRIE, RN
MARLIER, JF
JOHNSON, KA
BENKOVIC, SJ
[J]. BIOCHEMISTRY, 1985, 24 (15) : 4010 - 4018

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