IDENTIFICATION OF SHORT-CHAIN ALPHA-HYDROXYALDEHYDES PRODUCED BY LIPID-PEROXIDATION IN BOVINE LIVER

被引：14

作者：

LOIDL, A

SPITELLER, G

机构：

[1] Bayreuth, W-8580, Universitätsstrasse 30

来源：

ORGANIC MASS SPECTROMETRY | 1993年 / 28卷 / 03期

关键词：

D O I：

10.1002/oms.1210280305

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A method to detect short-chain alpha-hydroxyaldehydes in mammalian tissues is described. Aldehydes or their masked precursor molecules are converted into dithiolane derivatives. These are separated by thin-layer chromatography and registered by multiple ion monitoring after trimethylsilylation. Fragmentation of 2-(1'-trimethylsilyloxy)-1,3-dithiolanes was studied by using electron impact ionization.

引用

页码：153 / 156

页数：4

共 11 条

[1]

BLIGH EG, 1959, CAN J BIOCHEM PHYS, V37, P911

[2]

EMERIT J, 1989, CRC HDB FREE RADICAL, P177

[3]

ESTERBAUER H, 1985, FREE RADICALS LIVER, P29

[4] THIOBARBITURIC ACID-REACTIVE MALONDIALDEHYDE FORMATION DURING SUPEROXIDE-DEPENDENT, IRON-CATALYZED LIPID-PEROXIDATION - INFLUENCE OF PEROXIDATION CONDITIONS [J].