SYNTHESIS OF BIOACTIVE COMPOUNDS FROM ABUNDANT NATURAL-PRODUCTS .12. THE SYNTHESIS OF A NEW BENZOTHIAZINE DERIVATIVE, RELATED TO OXICAMS, SYNTHESIZED FROM NATURAL SAFROLE

被引：18

作者：

FRAGA, CAM ^{[1
]}

BARREIRO, EJ ^{[1
]}

机构：

[1] UNIV FED RIO DE JANEIRO, INST QUIM, BR-21944 RIO DE JANEIRO, BRAZIL

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1992年 / 29卷 / 06期

关键词：

D O I：

10.1002/jhet.5570290652

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the new derivatives, 2-methyl-6,7-methylenodioxy-2H-1,2-benzothiazin-3-one-4-(N-phenyl)carboxamide 1,1-dioxide (6a) from natural safrole (5) is described. The principal feature of this route is brevity and the high overall yield, producing the new analogue in ca. 35% from the natural product.

引用

页码：1667 / 1669

页数：3

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