ASPIDOSPERMA ALKALOIDS VIA CYCLIZATION OF SECODINE INTERMEDIATE - SYNTHESIS OF (+/-)-3-OXOVINCADIFFORMINE ETHYL-ESTER

被引：27

作者：

DANIELI, B ^{[1
]}

LESMA, G ^{[1
]}

PALMISANO, G ^{[1
]}

PASSARELLA, D ^{[1
]}

SILVANI, A ^{[1
]}

机构：

[1] CNR,CTR STUDIO SOSTANZE ORGAN NAT,I-20133 MILAN,ITALY

来源：

TETRAHEDRON | 1994年 / 50卷 / 23期

关键词：

D O I：

10.1016/S0040-4020(01)81347-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(+/-)-3-oxovincadifformine ethyl ester 14 has been synthesized through an intramolecular [4 pi+2 pi] cycloaddition of the 3-oxosecodine 13 first prepared in turn from the enamide 10 by dehydrogenation with benzeneseleninic anhydride. An insight into the conversion of 10 into 13 was gained, resulting in the suggestion of a plausible mechanistic pathway.

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页码：6941 / 6954

页数：14

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