SYNTHESIS AND ALKYLATION OF CIS-3-ALPHA-HYDROXYISOPROPYLINDANONE-2-CARBOXYLIC ACID LACTONE

被引：9

作者：

CAMPAIGNE, E

FRIERSON, MR

机构：

[1] Chemical Laboratories, Indiana University, Bloomington, Indiana

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1979年 / 16卷 / 02期

关键词：

D O I：

10.1002/jhet.5570160207

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Meldrum's acid adduct of isobutyrophenone was cyclized directly and in high yield to the title compound, which could then be alkylated at the 2‐position with methyl iodide or ethyl 6‐bromohexanoate. In the latter case, acid hydrolysis of the resultant ester gave the analogous acid, but alkaline hydrolysis resulted in ring opening of the indanone portion of the molecule. Copyright © 1979 Journal of Heterocyclic Chemistry

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页码：235 / 237

页数：3

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