FORMATION OF 4-ESTRENE-3,17-DIONE (19-NORANDROSTENEDIONE) BY PORCINE GRANULOSA-CELLS INVITRO IS INHIBITED BY THE AROMATASE INHIBITOR 4-HYDROXYANDROSTENEDIONE AND THE CYTOCHROME-P-450 INHIBITORS AMINOGLUTETHIMIDE PHOSPHATE AND KETOCONAZOLE

被引：20

作者：

KHALIL, MW

MORLEY, P

GLASIER, MA

ARMSTRONG, DT

LANG, T

机构：

[1] UNIV WESTERN ONTARIO,DEPT OBSTET & GYNAECOL,LONDON N6A 5A5,ONTARIO,CANADA

[2] UNIV WESTERN ONTARIO,DEPT PHYSIOL,LONDON N6A 5A5,ONTARIO,CANADA

[3] UNIV WESTERN ONTARIO,DEPT BIOCHEM,LONDON N6A 5A5,ONTARIO,CANADA

来源：

JOURNAL OF ENDOCRINOLOGY | 1989年 / 120卷 / 02期

关键词：

D O I：

10.1677/joe.0.1200251

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：251 / 260

页数：10

共 49 条

[1] AROMATIZATION OF ANDROSTENEDIONE BY HUMAN ADIPOSE-TISSUE STROMAL CELLS IN MONOLAYER-CULTURE [J].

ACKERMAN, GE ;

SMITH, ME ;

MENDELSON, CR ;

MACDONALD, PC ;

SIMPSON, ER .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1981, 53 (02) :412-417

[2] MECHANISTIC STUDIES ON C-19 DEMETHYLATION IN ESTROGEN BIOSYNTHESIS [J].

AKHTAR, M ;

CALDER, MR ;

CORINA, DL ;

WRIGHT, JN .

BIOCHEMICAL JOURNAL, 1982, 201 (03) :569-580

[3]

BAGGETT B, 1956, J BIOL CHEM, V221, P931

[4] AROMATASE INHIBITION AND ITS PHARMACOLOGIC IMPLICATIONS [J].

BRODIE, AMH .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (18) :3213-3219

[5] EFFECT OF AN AROMATASE INHIBITOR, 4-HYDROXY-4-ANDROSTENE-3,17-DIONE, ON ESTROGEN-DEPENDENT PROCESSES IN REPRODUCTION AND BREAST-CANCER [J].

BRODIE, AMH ;

SCHWARZEL, WC ;

SHAIKH, AA ;

BRODIE, HJ .

ENDOCRINOLOGY, 1977, 100 (06) :1684-1695

[6] STUDIES ON MECHANISM OF ESTROGEN BIOSYNTHESIS .7. 2BETA-HYDROXYLATION OF ESTR-4-ENE-3,17-DIONE IN HUMAN PLACENTA, IN VITRO [J].

BRODIE, HJ ;

PILLAI, AK ;

HAY, CE .

BIOCHIMICA ET BIOPHYSICA ACTA, 1969, 187 (02) :275-&

[7] ESTROGEN BIOSYNTHESIS - CONCERNING THE OBLIGATORY INTERMEDIACY OF 2-BETA-HYDROXY-10-BETA-FORMYLANDROST-4-ENE-3,17-DIONE [J].

CASPI, E ;

WICHA, J ;

ARUNACHALAM, T ;

NELSON, P ;

SPITELLER, G .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (23) :7282-7283

[8] SERUM CONTAINS A PLATELET-DERIVED TRANSFORMING GROWTH-FACTOR [J].

CHILDS, CB ;

PROPER, JA ;

TUCKER, RF ;

MOSES, HL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (17) :5312-5316

[9] ENHANCEMENT OF FOLLICLE-STIMULATING HORMONE-INDUCED AROMATASE-ACTIVITY BY ANDROGENS IN CULTURED RAT GRANULOSA-CELLS [J].

DANIEL, SAJ ;

ARMSTRONG, DT .

ENDOCRINOLOGY, 1980, 107 (04) :1027-1033

[10] 19-NORANDROSTENEDIONE (4-ESTRENE-3, 17-DIONE) INHIBITS PORCINE OOCYTE MATURATION INVITRO [J].

DANIEL, SAJ ;

KHALIL, MW ;

ARMSTRONG, DT .

GAMETE RESEARCH, 1986, 13 (02) :173-184

← 1 2 3 4 5 →