EFFECT OF CHRONIC METOCLOPRAMIDE THERAPY ON SERUM PITUITARY-HORMONE CONCENTRATIONS

被引：16

作者：

TAMAGNA, EI

LANE, W

HERSHMAN, JM

CARLSON, HE

STURDEVANT, RAL

POLAND, RE

RUBIN, RT

机构：

[1] VET ADM WADSWORTH HOSP CTR,SERV MED,ENDOCRINOL SECT,LOS ANGELES,CA 90073

[2] VET ADM WADSWORTH HOSP CTR,SERV RES,GASTROENTEROL SECT,LOS ANGELES,CA 90073

[3] UNIV CALIF LOS ANGELES,HARBOR GEN HOSP,DEPT MED,LOS ANGELES,CA 90024

[4] UNIV CALIF LOS ANGELES,HARBOR GEN HOSP,DEPT PSYCHIAT,LOS ANGELES,CA 90024

来源：

HORMONE RESEARCH | 1979年 / 11卷 / 04期

关键词：

Metoclopramide; Pituitary function; Prolactin;

D O I：

10.1159/000179051

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effect of chronic (3-9 months) therapy with metoclopramide on scrum levels of pituitary and thyroid hormones was studied in 4 males and 1 female. The mean serum prolactin concentration during metoclopramide therapy was significantly higher than after discontinuation of metoclopramide. Scrum prolactin concentrations increased acutely after each dose of metoclopramide, and gradually returned to normal by 6-12 h. There were no significant differences in the serum TSH, T3T4, GH, and gonadotrophin levels during and after metoclopramide administration. In the male subjects the mean serum testosterone was normal, but significantly lower during metoclopramide therapy. © 1979 S. Karger AG, Basel.

引用

页码：161 / 169

页数：9

共 17 条

[1] PLASMA THYROTROPIN, THYROXINE, AND TRIIODOTHYRONINE RELATIONSHIPS IN MAN [J].