A83543A-D, UNIQUE FERMENTATION-DERIVED TETRACYCLIC MACROLIDES

被引:102
作者
KIRST, HA [1 ]
MICHEL, KH [1 ]
MARTIN, JW [1 ]
CREEMER, LC [1 ]
CHIO, EH [1 ]
YAO, RC [1 ]
NAKATSUKASA, WM [1 ]
BOECK, L [1 ]
OCCOLOWITZ, JL [1 ]
PASCHAL, JW [1 ]
DEETER, JB [1 ]
JONES, ND [1 ]
THOMPSON, GD [1 ]
机构
[1] DOWELANCO, DISCOVERY RES, GREENFIELD, IN 46140 USA
关键词
D O I
10.1016/S0040-4039(00)93474-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A multi-factored complex of structurally-unique macrolides was isolated from culture broths of a new species of Saccharopolyspora. The core structure consists of a 5,6,5-cis-anti-trans-tricyclic ring system fused to a 12-membered macrocyclic lactone, which is further substituted by an amino- and a neutral sugar.
引用
收藏
页码:4839 / 4842
页数:4
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