TOTAL SYNTHESIS OF PLAGIOCHIN-C AND PLAGIOCHIN-D, MACROCYCLIC BIS(BIBENZYL) CONSTITUENTS OF PLAGIOCHILA-ACANTOPHYLLA

被引：33

作者：

KESERU, GM

MEZEYVANDOR, G

NOGRADI, M

VERMES, B

KAJTARPEREDY, M

机构：

[1] HUNGARIAN ACAD SCI,ALKALOID CHEM RES GRP,POB 91,H-1521 BUDAPEST,HUNGARY

[2] HUNGARIAN ACAD SCI,CENT RES INST CHEM,H-1525 BUDAPEST,HUNGARY

来源：

TETRAHEDRON | 1992年 / 48卷 / 05期

关键词：

PLAGIOCHINS; BIS(BIBENZYLS); SYNTHESIS; MACROCYCLES; WURTZ REACTION;

D O I：

10.1016/S0040-4020(01)88193-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Plagiochins C (3) and D (4) were synthesized by convergent schemes. Rings C and B were joined by Ullman ether synthesis, the aryl-aryl bond between rings A and D was formed by Pd(0)-catalysed coupling of an arylboronic acid (ring D) and a bromobenzoic ester (ring A). Ring C and D were linked by the Wittig reaction, while final ring closure was effected by tetraphenylethene assisted Wurtz reaction.

引用

页码：913 / 922

页数：10

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