POSITIVE INTERACTION OF ETHANOL AND KAVA RESIN IN MICE

被引:40
作者
JAMIESON, DD
DUFFIELD, PH
机构
[1] School of Physiology and Pharmacology, University of New South Wales, Kensington, New South Wales
关键词
alcohol; ethanol; kava sedation; toxicity;
D O I
10.1111/j.1440-1681.1990.tb01350.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
1. The lipid soluble extract of the psychoactive beverage kava has hypnosedative properties which can be measured by the length of time that the righting reflex is lost. 2. Ethanol and the lipid soluble extract (kava resin) have been shown greatly to increase each others hypnotic action in mice. Ethanol also increases the toxicity of kava markedly. 3. This interaction of kava and alcohol has important clinical and social consequences since, in contrast to traditional usage, kava is now often taken in conjunction with alcoholic drinks. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
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页码:509 / 514
页数:6
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