SYNERGISM BETWEEN CHLORHEXIDINE AND POLYMYXINS AGAINST PSEUDOMONAS-AERUGINOSA

被引：9

作者：

ALNAJJAR, AR ^{[1
]}

QUESNEL, LB ^{[1
]}

机构：

[1] UNIV MANCHESTER,DEPT BACTERIOL & VIROL,MANCHESTER M13 9PT,LANCASHIRE,ENGLAND

来源：

JOURNAL OF APPLIED BACTERIOLOGY | 1979年 / 47卷 / 03期

关键词：

D O I：

10.1111/j.1365-2672.1979.tb01208.x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Chlorhexidine acts synergistically with the polymyxins B and E causing increased and rapid release of cell contents from Pseudomonas aeruginosa. While the polymyxin target molecule is phospholipid, evidence is provided for the proposal that the primary target for Chlorhexidine action is a protein component of the cytoplasmic membrane. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：469 / 476

页数：8

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