ONE-DIMENSIONAL PROTON-CARBON CORRELATIONS FOR THE STRUCTURE DETERMINATION OF NATURAL-PRODUCTS

The selective INEPT technique, a one-dimensional, J-modulated, proton-carbon correlation technique, has proved to be a very powerful tool for both unambiguous carbon and proton spectral assignment, as well as providing critical carbon framework information. In this brief review we offer some examples of recent work in our laboratories which demonstrates the power of the technique, particularly when sample size is limited.