F-19 NUCLEAR MAGNETIC-RESONANCE INVESTIGATION OF THE NON-COVALENT AND COVALENT BINARY COMPLEXES OF 5-FLUORODEOXYURIDYLATE AND LACTOBACILLUS-CASEI THYMIDYLATE SYNTHETASE

被引：41

作者：

LEWIS, CA ^{[1
]}

ELLIS, PD ^{[1
]}

DUNLAP, RB ^{[1
]}

机构：

[1] UNIV S CAROLINA,DEPT CHEM,COLUMBIA,SC 29208

来源：

BIOCHEMISTRY | 1980年 / 19卷 / 01期

关键词：

D O I：

10.1021/bi00542a018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：116 / 123

页数：8

共 34 条

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[2] CALORIMETRIC STUDY OF BINDING OF 2'-DEOXYURIDINE-5'-PHOSPHATE AND 5-FLUORO-2'-DEOXYURIDINE-5'-PHOSPHATE TO THYMIDYLATE SYNTHETASE [J].

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LANGERMAN, N ;

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[3] ELUCIDATION OF DETAILED STRUCTURES OF NATIVE AND DENATURED TERNARY COMPLEXES OF THYMIDYLATE SYNTHETASE VIA F-19 NMR [J].

BYRD, RA ;

DAWSON, WH ;

ELLIS, PD ;

DUNLAP, RB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (24) :7478-7486

[4] F-19 NUCLEAR MAGNETIC-RESONANCE INVESTIGATION OF TERNARY COMPLEX FORMED BETWEEN NATIVE THYMIDYLATE SYNTHETASE, 5-FLUORO-2'-DEOXYURIDYLATE, AND 5,10-METHYLENETETRAHYDROFOLATE [J].

BYRD, RA ;

DAWSON, WH ;

ELLIS, PD ;

DUNLAP, RB .

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[5] MULTINUCLEAR 18-MM PROBE FOR VARIAN XL-100-15 NMR SPECTROMETER [J].

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[6]

BYRD RA, 1977, THESIS U S CAROLINA

[7]

CUSHLEY RJ, 1968, TETRAHEDRON LETT, P5393

[8] THYMIDYLATE SYNTHETASE - TARGET ENZYME IN CANCER CHEMOTHERAPY [J].

DANENBERG, PV .

BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 473 (02) :73-92

[9]

DANENBERG PV, 1975, FED PROC, V34, P522

[10]

DANENBERG PV, 1974, BIOCHEMISTRY, V13, P925

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