EXPRESSION OF THE EPIDERMAL GROWTH-FACTOR RECEPTOR IN FETAL KIDNEY

被引：20

作者：

GOODYER, PR

CYBULSKY, A

GOODYER, C

机构：

[1] Division of Pediatric Nephrology, Montreal Children's Hospital, McGill University, Montreal, H3H 1P3, Quebec, Room E-222

[2] Division of Nephrology, Royal Victoria Hospital, McGill University, Montreal, Quebec

[3] Division of Pediatric Endocrinology, Montreal Children's Hospital, McGill University, Montreal, Quebec

来源：

PEDIATRIC NEPHROLOGY | 1993年 / 7卷 / 05期

关键词：

EPIDERMAL GROWTH FACTOR RECEPTOR; FETAL KIDNEY; NEPHRON GENERATION;

D O I：

10.1007/BF00852567

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Formation of the human kidney begins at the 6th week of fetal life when the first generations of nephrons are generated from foci of metanephric mesenchyme through contact with the branches of the ureteric bud. This process requires a proliferative burst which must be tightly regulated by local signals. In this report, we review the evidence that the epidermal growth factor receptor molecule is an important arbiter of these events.

引用

页码：612 / 615

页数：4

共 16 条

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