RECENT DEVELOPMENTS IN IMMUNOTOXIN THERAPY

被引：41

作者：

GHETIE, MA ^{[1
]}

VITETTA, ES ^{[1
]}

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT MICROBIOL,DALLAS,TX 75235

来源：

CURRENT OPINION IN IMMUNOLOGY | 1994年 / 6卷 / 05期

关键词：

D O I：

10.1016/0952-7915(94)90073-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immunotoxin (IT) research has been ongoing for 15 years. During the past 2 years, work has focused on several areas: on improvements and developments in first- and second-generation ITs; the preparation of new immunotoxin constructs with anti-tumor activity; novel animal models for preclinical evaluation of immunotoxins; and clinical trials, which are now entering Phase II or III in humans.

引用

页码：707 / 714

页数：8

共 77 条

[1] AMLOT PL, 1993, BLOOD, V82, P2624
[2] COMBINED USE OF AN IMMUNOTOXIN AND CYCLOSPORINE TO PREVENT BOTH ACTIVATED AND QUIESCENT PERIPHERAL-BLOOD T-CELLS FROM PRODUCING TYPE-1 HUMAN-IMMUNODEFICIENCY-VIRUS
BELL, KD
RAMILO, O
VITETTA, ES
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (04) : 1411 - 1415
[3] POTENT ANTI-CD5 RICIN-A CHAIN IMMUNOCONJUGATES FROM BACTERIALLY PRODUCED FAB' AND F(AB')2
BETTER, M
BERNHARD, SL
LEI, SP
FISHWILD, DM
LANE, JA
CARROLL, SF
HORWITZ, AH
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (02) : 457 - 461
[4] ERADICATION OF LARGE SOLID TUMORS IN MICE WITH AN IMMUNOTOXIN DIRECTED AGAINST TUMOR VASCULATURE
BURROWS, FJ
THORPE, PE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (19) : 8996 - 9000
[5] BURROWS FJ, 1992, CANCER RES, V52, P5954
[6] TARGETED KILL - FROM UMBRELLAS TO MONOCLONAL-ANTIBODIES
BYERS, VS
BALDWIN, RW
[J]. JOURNAL OF CLINICAL IMMUNOLOGY, 1992, 12 (06) : 391 - 405
[7] CHARI RVJ, 1992, CANCER RES, V52, P127
[8] CHAUDRY GJ, 1993, J BIOL CHEM, V268, P9437
[9] ANTI-CD6-BLOCKED RICIN - AN ANTI-PAN T-CELL IMMUNOTOXIN
COLLINSON, AR
LAMBERT, JM
LIU, Y
ODEA, C
SHAH, SA
RASMUSSEN, RA
GOLDMACHER, VS
[J]. INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 1994, 16 (01): : 37 - 49
[10] THE ASPERGILLUS TOXIN RESTRICTOCIN IS A SUITABLE CYTO-TOXIC AGENT FOR GENERATION OF IMMUNOCONJUGATES WITH MONOCLONAL-ANTIBODIES DIRECTED AGAINST HUMAN CARCINOMA-CELLS
CONDE, FP
ORLANDI, R
CANEVARI, S
MEZZANZANICA, D
RIPAMONTI, M
MUNOZ, SM
JORGE, P
COLNAGHI, MI
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1989, 178 (03): : 795 - 802

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