CYTOTOXIC LYMPHOCYTES - 2 WAYS TO KILL TARGET-CELLS

被引：38

作者：

HENKART, PA ^{[1
]}

SITKOVSKY, MV ^{[1
]}

机构：

[1] NIAID,IMMUNOL LAB,BETHESDA,MD 20814

来源：

CURRENT BIOLOGY | 1994年 / 4卷 / 10期

关键词：

D O I：

10.1016/S0960-9822(00)00207-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Of the two pathways implicated in target-cell damage by cytotoxic lymphocytes, secretory granule exocytosis seems to dominate in anti-viral immunity whereas the Fas pathway may regulate immune responses.

引用

页码：923 / 925

页数：3

共 13 条

[1] CYTOTOXIC LYMPHOCYTES REQUIRE GRANZYME-B FOR THE RAPID INDUCTION OF DNA FRAGMENTATION AND APOPTOSIS IN ALLOGENEIC TARGET-CELLS
HEUSEL, JW
WESSELSCHMIDT, RL
SHRESTA, S
RUSSELL, JH
LEY, TJ
[J]. CELL, 1994, 76 (06) : 977 - 987
[2] CYTOTOXICITY MEDIATED BY T-CELLS AND NATURAL-KILLER-CELLS IS GREATLY IMPAIRED IN PERFORIN DEFICIENT MICE
KAGI, D
LEDERMANN, B
BURKI, K
SEILER, P
ODERMATT, B
OLSEN, KJ
PODACK, ER
ZINKERNAGEL, RM
HENGARTNER, H
[J]. NATURE, 1994, 369 (6475) : 31 - 37
[3] MORGAN BP, 1989, BIOCHEM J, V264, P1
[4] NAKAJIMA H, 1994, J IMMUNOL, V152, P1057
[5] CYTOTOXIC LYMPHOCYTE-T MEDIATED LYSIS WITHOUT RELEASE OF SERINE ESTERASE
OSTERGAARD, HL
KANE, KP
MESCHER, MF
CLARK, WR
[J]. NATURE, 1987, 330 (6143) : 71 - 72
[6] A CENTRAL ROLE OF PERFORIN IN CYTOLYSIS
PODACK, ER
HENGARTNER, H
LICHTENHELD, MG
[J]. ANNUAL REVIEW OF IMMUNOLOGY, 1991, 9 : 129 - 157
[7] FAS INVOLVEMENT IN CA2+-INDEPENDENT T-CELL-MEDIATED CYTOTOXICITY
ROUVIER, E
LUCIANI, MF
GOLSTEIN, P
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (01) : 195 - 200
[8] MATURE T-CELLS OF AUTOIMMUNE LPR/LPR MICE HAVE A DEFECT IN ANTIGEN-STIMULATED SUICIDE
RUSSELL, JH
RUSH, B
WEAVER, C
WANG, RD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (10) : 4409 - 4413
[9] PREMATURE P34(CDC2) ACTIVATION REQUIRED FOR APOPTOSIS
SHI, L
NISHIOKA, WK
THNG, J
BRADBURY, EM
LITCHFIELD, DW
GREENBERG, AH
[J]. SCIENCE, 1994, 263 (5150) : 1143 - 1145
[10] SITKOVSKY MV, 1993, CYTOTOXIC CELLS RECO

← 1 2 →