STEREOCOMPLEMENTARY CONSTRUCTION OF 2-ETHYNYL-3-HYDROXYTETRAHYDROFURAN DERIVATIVES VIA ENDO-MODE RING CLOSURE OF 3,4-EPOXY-6-SUBSTITUTEDHEX-5-YN-1-OLS

被引：20

作者：

MUKAI, C

SUGIMOTO, Y

IKEDA, Y

HANAOKA, M

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 10期

关键词：

D O I：

10.1039/c39940001161

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Treatment of 3,4-epoxy-6-substitutedhex-5-yn-1-ols with BF3.OEt(2) gave-the endo-mod cyclization products with inversion of stereochemistry, whereas conversion of the epoxides to the corresponding hexacarbonyldicobalt complexes, followed by Lewis-acid treatment provided the endo-mode products with retention of configuration at the newly formed stereogenic centre.

引用

页码：1161 / 1162

页数：2

共 15 条

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