EFFICIENT SYNTHESIS OF DIASTEREOSELECTIVELY LABELED (3S)-[4-C-13]-L-VALINE, AND REGIOSELECTIVELY LABELED [3-(CH3)-C-13]-L-ISOLEUCINE HYDROCHLORIDES

被引：8

作者：

HUMPHREY, JM ^{[1
]}

HART, JA ^{[1
]}

CHAMBERLIN, AR ^{[1
]}

机构：

[1] UNIV CALIF IRVINE,DEPT CHEM,IRVINE,CA 92717

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 12期

关键词：

D O I：

10.1016/0960-894X(95)00214-E

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Diastereoselectively labeled (3S)-[4-C-13]-L valine and regioselectively labeled [3-(CH3)-C-13]-L-isoleucine hydrochlorides were synthesized in 54% and 62% respective overall yields from L-aspartic acid.

引用

页码：1315 / 1320

页数：6

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