OVALBUMIN GENE REGION - COMMON FEATURES IN THE ORGANIZATION OF 3 GENES EXPRESSED IN CHICKEN OVIDUCT UNDER HORMONAL-CONTROL

被引：138

作者：

ROYAL, A

GARAPIN, A

CAMI, B

PERRIN, F

MANDEL, JL

LEMEUR, M

BREGEGEGRE, F

GANNON, F

LEPENNEC, JP

CHAMBON, P

KOURILSKY, P

机构：

[1] INST PASTEUR, BIOL MOLEC GRP,UNITE GENIE GENET,CNRS, EQUIPE RECH 201, F-75015 PARIS, FRANCE

[2] CNRS, GENET MOLEC EUCARYOTES LAB, F-67000 STRASBOURG, FRANCE

[3] FAC MED STRASBOURG, INSERM, UNITE BIOL MOLEC & GENIE GENET 184, F-67085 STRASBOURG, FRANCE

来源：

NATURE | 1979年 / 279卷 / 5709期

关键词：

D O I：

10.1038/279125a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Two large DNA fragments overlapping the chicken ovalbumin gene have been isolated by molecular cloning. Analysis of these fragments provided a map of a 46,000-Base pair region of the chicken genome. This region contains the complete ovalbumin gene (including its mRNA leader-coding sequence) and at least two other genes of unknown function. All three genes are orientated in the same direction and their expression in chicken oviduct is under hormonal control. The three genes share some sequence homologies, suggesting that duplications have occurred in the ovalbumin gene region in the course of evolution. © 1979 Nature Publishing Group.

引用

页码：125 / 132

页数：8

共 34 条

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