TRANSITION OF ANTIBODY TO HEPATITIS-C VIRUS FROM CHRONIC HEPATITIS TO HEPATOCELLULAR-CARCINOMA

被引：28

作者：

KIYOSAWA, K

TANAKA, E

SODEYAMA, T

FURUTA, K

USUDA, S

YOUSUF, M

FURUTA, S

机构：

[1] Second Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, 390, 3-1-1, Asahi

来源：

JAPANESE JOURNAL OF CANCER RESEARCH | 1990年 / 81卷 / 11期

关键词：

Anti‐HCV; Chronic hepatitis; Hepatitis C virus (HCV); Hepatocellular carcinoma;

D O I：

10.1111/j.1349-7006.1990.tb02517.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Fifty‐eight patients with chronic hepatitis C were followed for more than 7 years. Of them, 10 patients were found to develop hepatocellular carcinoma, 14 to develop liver cirrhosis, 30 to sustain chronic hepatitis, and 4 to show subsidence of hepatitis. Antibody to hepatitis C virus (anti‐HCV) disappeared from the 4 patients whose hepatitis subsided, but it persisted in the remaining 54 patients. The mean titer of anti‐HCV was almost the same at the stages of chronic hepatitis and of cancer in the 10 patients who developed hepatocellular carcinoma. These results indicate that chronic infection of hepatitis C virus may lead to hepatocellular carcinoma. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：1089 / 1091

页数：3

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