RELEASE OF 2-AMINOFLUORENE FROM N-(DEOXYGUANOSIN-8-YL)-2-AMINOFLUORENE BY HYDRAZINOLYSIS

被引：8

作者：

BAKTHAVACHALAM, J

ABDELBAKY, S

GIESE, RW

机构：

[1] NORTHEASTERN UNIV,COLL PHARM & ALLIED HLTH PROFESS,DEPT MED CHEM,BOSTON,MA 02115

[2] NORTHEASTERN UNIV,BARNETT INST CHEM ANAL & MAT SCI,BOSTON,MA 02115

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 538卷 / 02期

关键词：

D O I：

10.1016/S0021-9673(01)88867-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

High temperature (160-degrees-C) hydrazinolysis is demonstrated to be a useful chemical transformation reaction for releasing an aminopolyaromatic hydrocarbon, 2-aminofluorene, from a parent DNA adduct, N-(deoxyguanosin-8-yl)-2-aminofluorene.

引用

页码：447 / 451

页数：5

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