RECENT ADVANCES IN CYTOMETRY, CYTOGENETICS AND MOLECULAR-GENETICS OF THYROID-TUMORS AND TUMOR-LIKE LESIONS

被引：23

作者：

SOARES, P

SOBRINHOSIMOES, M

机构：

[1] FAC MED PORTO, DEPT PATHOL, P-4100 OPORTO, PORTUGAL

[2] UNIV PORTO, IPATIMUP, INST MOLEC PATHOL & IMMUNOL, OPORTO, PORTUGAL

来源：

PATHOLOGY RESEARCH AND PRACTICE | 1995年 / 191卷 / 04期

关键词：

THYROID; GOITER; ADENOMA; CARCINOMA; FLOW CYTOMETRY; IMAGE CYTOMETRY; MORPHOMETRY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; CYTOGENETICS; MOLECULAR GENETICS; ONCOGENES; ANTIONCOGENES;

D O I：

10.1016/S0344-0338(11)80884-8

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

In this review we summarize the most recent advances of flow and image cytometry, cytogenetics and molecular genetics of tumours and tumour-like lesions of the thyroid, especially focusing on the putative relationship between nodular goitres and adenomas, the differential diagnosis of benign and malignant neoplasms and the pathogenesis and prognosis of carcinomas. Data obtained by in situ hybridization and immunohistochemical detection of proliferative markers, metal binding proteins and oncogenes, anti-oncogenes, growth factors and growth factor receptors are also used whenever appropriate.

引用

页码：304 / 317

页数：14

共 151 条

[1] EXPRESSION OF ONCOGENES IN THYROID-TUMORS - COEXPRESSION OF C-ERBB2/NEU AND C-ERBB [J].