PRECONDITIONING STIMULI AND INADVERTENT PRECONDITIONING

被引：17

作者：

KLONER, RA

PRZYKLENK, K

WHITTAKER, P

HALE, S

机构：

来源：

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY | 1995年 / 27卷 / 02期

关键词：

PRECONDITIONING; ISCHEMIA; HYPOXIA; CORONARY OCCLUSION;

D O I：

10.1016/0022-2828(95)90079-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There are several factors besides brief episodes of total coronary occlusion which can provide sufficient stress to result in a preconditioning-like effect on the size of a myocardial infarction. Partial coronary artery stenosis, hypoxia, stretch, catecholamines, rapid pacing, and certain pharmacologic therapies may provide preconditioning stimuli, These same factors as well as mechanical complications in which a coronary artery is briefly occluded or stenosed prior to a subsequent coronary occulsion may lead to inadvertent preconditioning and confound the results of experimental cardiology studies.

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收藏

页码：743 / 747

页数：5

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